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Wednesday, June 6, 2007

What is Peritoneal Mesothelioma?

Peritoneal Mesothelioma is a tumor of the membrane Peritoneum. The peritoneum is a thin membrane in the organs in the abdomen consisting of mesothelial cells.

Peritoneal Mesothelioma is associated to coming about from having previous exposure to asbestos, and in many cases is found through routine abdominal xrays and CT scans showing something different than normal.

Peritoneal Mesothelioma can stay dormant in your body for many years, before it will be seen, and for this reason many people years after they have been exposed to asbestos will be diagnosed with Peritoneal Mesothelioma. About 20% of all mesotheliomas are Peritoneal Mesothelioma, and they can be of two types: malignant and benign.

What are the Symptons of Peritoneal Mesothelioma?


- abdominal pains
- weakness
- weight loss
- loss of appetite
- nausea
- abdominal swelling

The symptoms become more severe over time and should be checked out by a doctor. If they do not, they will cause increasing pressure on your abdomen organs, causing much discomfort, and will lead to bowel obstruction and distention.

How is peritoneal mesothelioma diagnosed? A peritoneoscopy is performed, and if there is a reason to be concerned, a biopsy is performed. A biopsy is the process of taking a piece of tissue to be given to a pathologist for analysis. The pathologist uses a microscope to analyse the tissue and make the actual diagnosis.

Currently, it is still unknown why Asbestos causes the mesothelial cells to be cancerous, and it is unsure how many fibers are needed for the tumor to occur. Many treatments exist for peritoneal mesothelioma, however a cure has yet to be found.

What are some of the treatments available for Peritoneal Mesothelioma?
- chemotherapy
- radiation therapy
- surgery.

If you are feeling any of the symptoms noted above, ensure you have it checked out early. The earlier the diagnosis of Peritoneal Mesothelioma, the better chance the treatments will be effective.

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Mesothelioma - Your Basic Information

Mesothelioma is a form of cancer that is becoming more and more common. The most common cause of this cancer is exposure to asbestos. When constantly exposed with insufficient protection, asbestos dust and fibres affect the mesothelial cells which make up the mesothelium. The mesothelium is the outer lining that protects some of the body’s most vital organs such as the heart and lungs. The mesothelial cells become abnormal after lengthy periods of constant exposure to asbestos causing an array of problems.

Due to the latency period and symptoms of this cancer, mesothelioma is very difficult to diagnose. Mesothelioma takes decades to mature and develop fully and this is why many elderly men who were exposed to asbestos thirty years before are just discovering they have the cancer. A lot of these men are currently lodging multi-million dollar lawsuits against the companies that exposed them to the dangers of asbestos without sufficient protection.

The organs that are affected most by mesothelioma are the lungs. The most common type of mesothelioma which is called pleural mesothelioma affects the lining of the lungs and can cause symptoms such as coughing, breathing and swallowing difficulties, shortness of breath and fever. Another area that can be affected by mesothelioma is the abdomen. This is less common and this is known as peritoneal mesothelioma. Symptoms of peritoneal mesothelioma include nausea and vomiting, weight loss, fever, bowel obstruction, loss of appetite and general pain in the stomach area. The last and least common type of mesothelioma is known as pericardial mesothelioma and it affects the heart and the tissue surrounding it. Symptoms of this form of the cancer include palpitations, breathing difficulties and persistent coughing. Generally, the symptoms of mesothelioma are typical of many other diseases and this makes it very difficult to diagnose.

There are treatments for mesothelioma although these are usually unsuccessful. If the cancer is treated aggressively in its early stages then there is a good chance of a patient surviving. However, due to the difficulty to diagnose mesothelioma, the cancer is not normally found until it is too late. Treatments that are used for mesothelioma include surgery, radiation therapy, palliative therapy and chemotherapy. Research for additional treatment of mesothelioma is being done at various cancer centers all over the United States as well as by pharmaceutical companies.

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Mesothelioma - an Asbestos Related Lung Cancer

Mesothelioma is a form of cancer located in the lining of either the lungs, abdomen or the heart. These linings are thin layers of tissue covering the organ.

The pleura is the tissue covering the lungs and the wall of the chest cavity which cushions and protects the lungs. The peritoneum lines the abdominal wall and surrounds most of the organs in the abdomen. The pericardium is the tissue surrounding the heart.

Mesothelioma is a rare but very serious cancer. There are three types of mesothelioma based on the types of cancerous cells. The most common type is epithelioid and consists of 50-70% of total cases and has the best prognosis. The second type is called sarcomatoid, consists of 10-20 % of mesothelioma cases and is more unpredictable in nature. The third type of mesothelioma is called biphasic, it is a combination of the other two types and consists of 20-35% of all cases.

There are an estimated 2000-3000 new cases of mesothelioma in the United States every year. The majority of these cases begin in the chest wall (pleural mesothelioma), a few start in the abdomen (peritoneal mesothelioma) and very rare are the cases starting in the lining surrounding the heart (pericardial mesothelioma).

The pleura is a thin lining of mesothelial cells. There are two pleuras in the chest, the parietal pleura and the visceral pleura. The parietal pleura lines the chest wall including the inside of the ribs, diaphragm and pericardium. The visceral pleura covers the lungs and filters fluid to and from the chest. If the pleura becomes diseases it is not effective at eliminating fluid from the chest resulting in pleural effusion or too much fluid in the chest.

Mesothelioma is usually the result of exposure to asbestos. Most people who are diagnosed with mesothelioma have had jobs where they breathed asbestos fibers. It may take up to 60 years from the time of asbestos exposure until mesothelioma develops.

Although rare, mesothelioma is a serious form of cancer which is often in its advanced stage when a diagnosis is made. In general, prognosis for mesothelioma patient is poor, however, some patients live with the disease for a long time. As mentioned earlier, the type of mesothelioma has an impact on the prognosis, as well as, the age of the patient, how much tumor has developed and if treatment is rendered. There are many variables in evaluating a mesothelioma case, so only the patients doctor can determine the best treatment and possible prognosis on an individual basis.

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